Left: Ordinary mice with many senescent cells in the body; Right: Mice depleted of senescent cells (Dasatinib + Quercetin)
How many "anti-aging drugs" are qualified in the laboratory? There are very few that can enter the human clinic. Dasatinib + quercetin therapy has entered the second clinical phase and is the No. 1 seed in the treatment of senescent cells. Dasatinib is a kind of leukemia medicine. Quercetin is a nutrient that naturally exists in food, and belongs to polyphenols, flavonoids, and flavonols.
The chemical structure of quercetin ↑
1. The liver is the body's "detoxification" organ, but overwork can damage the liver. Quercetin has the effect of detoxification and liver protection. The poisons it can decompose include industrial raw materials and biochemical experimental reagents. Quercetin is also a medicine for curing diseases, and even daily necessities in life.
2. The principle of quercetin protecting nerves and improving cognitive ability and memory lies in its powerful antioxidant and anti-inflammatory effects.
3. Protect blood vessels and cardiomyocytes.
4. Quercetin can prevent cancer and play a role in adjuvant therapy for individuals with cancer.
5. Eating foods rich in quercetin can reduce the damage of free radicals induced by light on the skin. And quercetin is a kind of bioactive plant extracts. The external application of quercetin extracted from plants can immediately relieve the redness and inflammation caused by sunburn. Injecting or applying quercetin cream can help the skin resist UVA and UVB damage, reduce oxidative stress, and prevent collagen degradation.
6. Benefits of taking quercetin is that can improve our body's immunity, and it can also strengthen the resistance to several specific viruses, including HIV and herpes viruses.
7. Quercetin, as an anti inflammatory plant extract, has powerful anti-inflammatory and antihistamine properties, which can help relieve symptoms of nasal allergies.
As a highly effective and active biologically active molecule, quercetin will definitely interact with some drugs, including:
1. Blood thinners that reduce the ability of blood to clot, such as warfarin;
2. Chemotherapeutic drugs doxorubicin and cisplatin;
3. Corticosteroids, such as prednisone, dexamethasone, etc.;
4. Drugs metabolized by the liver: Quercetin slows down the process of liver metabolism and may enhance the efficacy and side effects of drugs such as cyclosporine;
5. Quinolone antibiotics: norfloxacin, ofloxacin and the like.