Apigenin Cancer Dosage In Cancer Chemoprevention

Cancer prevalence patterns occur within regions as populations age or gradually urbanize. Since changes in dietary habits can affect cancer rates, immigration also contributes to this change. These epidemiological findings strongly suggest that cancer incidence is largely preventable by environmental factors, including diet.

Cancer can be largely prevented through diet by increasing your intake of fruits and vegetables. Can be treated with apigenin with cancer dosage to fight cancer. Apigenin cancer dosage is a naturally occurring plant flavonoid (4', 5, 7,-trihydroxyflavonoid) found in large amounts in common fruits and vegetables, including parsley, onions, oranges, tea, chamomile, wheat sprouts and some seasoning. Apigenin anticancer therapy has been shown to have significant anti-inflammatory, antioxidant and anticancer properties. In the past few years, significant progress has been made in studying the biological effects of apigenin at the cellular and molecular levels. Appropriate amount of apigenin cancer dosage has chemopreventive effect, and it has great development potential as a chemopreventive agent for apigenin anticancer therapy.  Kindarco biotech co,ltd , as a prefessional plant extract supplier in China, can promise to provide apigenin with high quality.

Apigenin breast cancer: from chemistry to medicine

Breast cancer is one of the most common causes of death in women worldwide. Metabolic disorders, alcohol consumption, hormone replacement therapy, genetic predisposition, and infertility are well-known risk factors for breast cancer. Surgery, radiation, and chemotherapy are limited treatment options for breast cancer. Therefore, there is a growing need to find new chemopreventive agents that may be effective in preventing and/or managing breast cancer. Natural products such as flavonoids provide a variety of anticancer compounds that can be used to prevent or treat breast cancer. Numerous experimental and epidemiological studies support the role of dietary phytochemicals in preventing this disease. Numerous studies have shown that apigenin has powerful antioxidant, anti-inflammatory and anticancer properties. Determining the therapeutic potential of apigenin apigenin extract in breast cancer by critical analysis of data from 5 countries.

Apigenin and prostate cancer chemoprevention

Significant differences in prostate cancer incidence in several regions of the world suggest that dietary factors may influence biological processes associated with prostate carcinogenesis. To reduce the incidence of this disease, chemoprevention through dietary intervention appears to be a practical and encouraging approach. What is the relationship between apigenin and prostate cancer? Laboratory studies in cell culture systems have shown that apigenin, a plant flavonoid abundant in fruits and vegetables, protects against a variety of human cancers. The relationship between apigenin and prostate cancer is that apigenin causes a selective response of normal cells to prostate cancer cells, inhibits cell growth, induces apoptosis, and in androgen-dependent and androgen-independent human prostate cancer cells, cells The GO-G1 phase of the cycle stalls. These new findings were designed to study the effect of oral apigenin on prostate tumorigenesis in vivo.

Apigenin for pancreatic cancer chemoprevention

Many chemotherapeutic agents have been used to treat pancreatic cancer without success. Apigenin Pancreatic Cancer Chemoprevention: Apigenin, a pure natural plant extract that has been shown to inhibit the growth of certain cancer cell lines, apigenin inhibits cyclin B-related cdc2 activity and G2/M phase arrest To inhibit the growth of pancreatic cancer cells, it may be a valuable drug for the treatment or prevention of pancreatic cancer.

Apigenin is a highly selective bioflavonoid compound, which can induce selective apoptosis of cancer cells in vivo. Like other bioflavonoid compounds, apigenin can reduce oxidative stress, induce cell cycle inhibition, improve the efficacy of liver detoxification enzymes, and has certain anti-inflammatory effects.

Experimental animal studies have shown that apigenin cancer dosage apigenin has anti-mutagenic properties, can respond to exogenous toxins and bacteria, and plays direct roles in metal chelation, free radical scavenging, and induction of phase II detoxifying enzymes such as glutathione. Apigenin cancer dosage is also an inhibitor of ornithine decarboxylase, which may promote the growth of certain tumors.

Apigenin, which is present in the body, also seems to have an acute protective effect against carcinogens.

Other apigenin receptor targets that apigenin cancer dosage may influence carcinogenicity include heat shock protein, telomerase, fatty acid synthase, aryl hydrocarbon receptor, casein kinase 2α, HER2/ NEU, and matrix metalloproteinases. It is also a relatively weak inhibitor of xanthine oxidase.

So far, professors believed that there is little evidence that apigenin, which has benefits in most cancers, promotes adverse metabolic reactions in the body when consumed as part of a normal diet.

reference: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629766/

                 https://examine.com/supplements/apigenin/research/#interaction-with-cancer-metabolism